Log Side Effect
Menstrual / Bleeding
Recent History
Partner Observation
What did you notice?
Recent History
Summary for Doctor
Top 3 Symptoms by Highest Average Severity
| Rank | Symptom | Avg Severity | Count |
|---|
Overall Daily Severity
Average of all logged symptoms that day (patient + partner)
Symptom Trends (Patient)
Select up to 5 symptoms to compare trends
Text Summary
Short, readable highlights (color-coded)
Daily Notes
Side-by-side view of patient and partner notes for selected time period.
| Date | Patient Note | Partner Note |
|---|
Exercise Log
Patient exercise entries for selected time period.
| Date | Exercise |
|---|
Share with Doctor
Generate a read-only link that expires in 7 days. No login required for doctor.
Partner Management
View and manage partner access to your data.
Pending Invites
Current Partners
⚠️ This information is for educational purposes only and is not medical advice.
Always consult your doctor or pharmacist about your specific situation.
Common Side Effects
Occur in more than 10% of patients
- Hot flashes & night sweats — Sudden feelings of warmth, often with sweating
- Vaginal discharge or dryness — Changes in vaginal secretions
- Irregular periods — Changes in menstrual cycle or loss of periods
- Nausea — Feeling sick to your stomach, especially when starting treatment
- Fatigue & weakness — Feeling tired or having low energy
- Mood changes — Depression, anxiety, or emotional changes
- Weight gain or fluid retention — Edema (swelling), particularly in legs
- Headaches — Mild to moderate head pain
Less Common Side Effects
Occur in 1-10% of patients
- Insomnia — Difficulty sleeping
- Dizziness — Feeling lightheaded
- Skin rash — Skin irritation or itching
- Hair thinning — Partial hair loss (alopecia)
- Abdominal pain — Stomach discomfort
- Joint or muscle pain — Aches in joints and muscles
- Changes in libido — Decreased sexual interest
- Cataracts — Eye lens clouding (monitor vision)
⚠️ Rare but Serious Side Effects
Occur in less than 1% — Require immediate medical attention
- Blood clots (DVT) — Deep vein thrombosis; watch for leg pain, swelling, warmth, or redness
- Pulmonary embolism — Blood clot in lungs; sudden shortness of breath, chest pain
- Stroke — Sudden numbness, confusion, trouble speaking, severe headache
- Uterine/endometrial cancer — Unusual vaginal bleeding; report any bleeding to doctor
- Severe allergic reaction — Difficulty breathing, swelling of face/throat
- Vision problems — Blurred vision, retinal changes, color vision changes
- Liver problems — Yellowing of skin/eyes, dark urine, severe fatigue
Seek immediate medical care if you experience any of these symptoms.
Who Should Not Take Tamoxifen
- Pregnant women — Tamoxifen may cause birth defects; use non-hormonal contraception during treatment and 2 months after
- Breastfeeding women — Drug accumulates in breast milk; avoid during treatment and 3 months after
- Known allergy — Previous allergic reaction to tamoxifen or its components
- Taking warfarin — Concurrent warfarin use is contraindicated
- History of blood clots — Prior DVT or pulmonary embolism (for prevention use; may still be appropriate for cancer treatment)
Drug Interactions
Discuss all medications with your doctor
- CYP2D6 inhibitors — Paroxetine (Paxil), fluoxetine (Prozac), and some SSRIs reduce tamoxifen effectiveness
- Warfarin — Increases bleeding risk; contraindicated together
- Aromatase inhibitors — Anastrozole, letrozole; should not be used together
- Rifampin — Significantly reduces tamoxifen levels
- Cytotoxic agents — May increase thromboembolic risk
Foods/Beverages to Avoid
- Grapefruit & tangerines — May interfere with drug metabolism
- Alcohol — May reduce effectiveness and increase side effects
Sources
Information compiled from authoritative medical sources:
FDA Drug Label |
Cleveland Clinic |
NCBI StatPearls